Molecular Typing of Treponema pallidum in Ocular Syphilis
نویسندگان
چکیده
منابع مشابه
Agglutination of Treponema Pallidum in Human Syphilis
The results observed with this strain of Treponema pallidum may be stated as follows: 1. Normal human serum did not agglutinate this culture of Treponema pallidum in dilutions of 1:5 or higher; equal parts of treponema culture and normal serum (dilution 1:2) resulted in agglutination in about 50 per cent of the sera. With the strain of Treponema pallidum used in this study specific agglutinatio...
متن کاملMolecular typing of treponema pallidum clinical strains from Lisbon, Portugal.
A molecular system was used to subtype Portuguese Treponema pallidum clinical strains isolated from both skin lesions and blood. The study with this system constitutes the first typing study in a European country. Three T. pallidum subtypes were found: subtypes 14a (50%), 14d (45.2%), and 14f (4.8%). Further studies are needed to better characterize the isolates involved in syphilis outbreaks.
متن کاملStudies on Treponema Pallidum and Syphilis
Although antibodies can be produced by the immunization of animals with cultivated Treponema pallidum, and although these antibodies exert specific agglutinative and treponemicidal action upon the culture organisms, they possess, at least in the concentration so far obtained by us in rabbits and sheep, practically no action for virulent treponemata obtained directly from lesions. There seems to...
متن کاملStudies on Treponema Pallidum and Syphilis. Ii. Spiroch~ticidal Antibodies against Treponema Pallidum. by Hans
In a previous communication we have reported on the agglufinins which are formed in rabbits following systematic inoculation with concentrated culture material of Treponema pallidum. Incidentally it may be stated that a sheep has also been successfully used. The antigen used for the immunization of these animals was similar to that employed in the first agglutination experiments, except that we...
متن کاملDetection of Treponema pallidum in early syphilis by DNA amplification.
By using experimentally infected rabbits as a model for early syphilis, the applicability of in vitro DNA amplification was explored for detection of Treponema pallidum. It was determined that whole blood in heparin or EDTA (but not serum), lesion exudate, and punch biopsy as well as swabs of lesions are useful specimens for examination by the polymerase chain reaction. Swabs do not require spe...
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ژورنال
عنوان ژورنال: Sexually Transmitted Diseases
سال: 2016
ISSN: 1537-4521,0148-5717
DOI: 10.1097/olq.0000000000000478